June 22, 2020
A STAT3-selective targeted protein degrader decreases the immune-suppressive tumor microenvironment and drives anti-tumor activity in preclinical models
American Association for Cancer Research (AACR) Virtual Annual Meeting II
Other
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December 7, 2019
Small molecule-induced, selective STAT3 degradation leads to anti-tumor activity in STAT3-dependent heme malignancies
American Society of Hematology (ASH) Annual Meeting
Other
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October 26, 2019
Discovery of KYM-003, a potent and selective STAT3 degrader with anti-tumor activity in heme malignancies
AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
Other
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June 18, 2019
IRAK4 degraders for MYD88 mutant lymphoma
International Conference on Malignant Lymphoma (ICML)
Other
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March 29, 2019
KYM-001, first-in-class oral IRAK4 protein degraders, induce tumor regression in a xenograft model of MYD-88 mutant ABC DLBCL alone and in combination with BTK inhibition
American Association for Cancer Research (AACR) Annual Meeting
Other
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December 1, 2018
Targeted degradation of IRAK4 protein via heterobifunctional small molecules for treatment of MYD88 mutant lymphoma
American Society of Hematology (ASH) Annual Meeting
Other
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