Resource Library

Discover Kymera’s research and resources on our exciting platform, pipeline, and additional cutting-edge technologies.

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Related Resources

July 28, 2022

Utilizing degraders to Modulate B & T Cell Targets for Autoimmune Diseases

3rd B&T Cell-Mediated Autoimmune Disease Drug Development
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May 31, 2022

STAT3 degraders inhibit Th17 development and cytokine production resulting in profound inhibition of collagen-induced autoimmune murine arthritis

European Alliance of Associations for Rheumatology (EULAR) 2022 Annual Congress
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May 17, 2022

Kinetics of IRAK4 Degradation and Impact on Functional Response in Circulating Immune Cells and Skin Cell Subsets

Society for Investigative Dermatology (SID) 2022 Annual Meeting
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May 3, 2022

STAT3 Degraders Inhibit Cellular Activation, Cytokine Production, and Th17 Development, Resulting in Profound Inhibition of Autoimmunity in the MOG-EAE Model of CNS Inflammation

The American Association of Immunologists (AAI) Immunology2022(TM)
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May 3, 2022

Selective IRAK4 Degradation, Not Kinase Inhibition, Blocks TLR-activated NF-kB and p38 Signaling Leading to broad Cytokine Inhibition

The American Association of Immunologists (AAI) Immunology2022(TM)
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October 28, 2021

Considerations for E3 Ligase Pairing and Screening of Immune-Inflammation Targets

4th Annual TPD Summit
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October 27, 2021

Safety, PK and PD from Single Ascending Does Portion of KT-474 Phase 1 Trial in Healthy Volunteers

4th Annual TPD Summit
Hidradenitis Suppurativa (HS) Atopic Dermatitis (AD)
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October 26, 2021

TPD Workshop: De-risking Clinical Development of a Novel Protein Degrader

4th Annual TPD Summit
Hidradenitis Suppurativa (HS) Atopic Dermatitis (AD)
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September 21, 2021

Identification of Highly Potent and Selective Interleukin-1 Receptor Associates Kinase 4 (IRAK4) Degrader for the Treatment of Autoimmune Disease

European Protein Degradation Congress
Hidradenitis Suppurativa (HS) Atopic Dermatitis (AD)
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May 10, 2021

IRAK4 Degradation Abrogates Cytokine Release and Improves Disease Endpoints in Murine Models of IL-33/36- as well as Th17-driven Inflammation

American Association of Immunologists’ Virtual IMMUNOLOGY2021™ Annual Meeting
Hidradenitis Suppurativa (HS) Atopic Dermatitis (AD)
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