May 31, 2022
STAT3 degraders inhibit Th17 development and cytokine production resulting in profound inhibition of collagen-induced autoimmune murine arthritis
European Alliance of Associations for Rheumatology (EULAR) 2022 Annual Congress
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May 17, 2022
Kinetics of IRAK4 Degradation and Impact on Functional Response in Circulating Immune Cells and Skin Cell Subsets
Society for Investigative Dermatology (SID) 2022 Annual Meeting
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May 10, 2022
Non-Clinical Safety Considerations when Developing Targeted Protein Degraders
Applied Pharmaceutical Toxicology (APT) 2022
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May 3, 2022
Selective IRAK4 Degradation, Not Kinase Inhibition, Blocks TLR-activated NF-kB and p38 Signaling Leading to broad Cytokine Inhibition
The American Association of Immunologists (AAI) Immunology2022(TM)
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May 3, 2022
STAT3 Degraders Inhibit Cellular Activation, Cytokine Production, and Th17 Development, Resulting in Profound Inhibition of Autoimmunity in the MOG-EAE Model of CNS Inflammation
The American Association of Immunologists (AAI) Immunology2022(TM)
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April 27, 2022
Drugging Tissue Restricted E3 Ligases for TPD-based Precision Medicine
2nd Annual Ligase Targeting Drug Development Summit
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April 26, 2022
Chemically Harnessing Novel E3 Ligases Biology for Next-generation TPD Therapeutics
2nd Annual Ligase Targeting Drug Development Summit
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April 7, 2022
KT-253, a highly potent and selective heterobifunctional MDM2 degrader for the treatment of wildtype p53 tumors with superior potency and differentiated biological activity compared to small molecule inhibitors (SMI)
American Association for Cancer Research Annual Meeting
Liquid Tumors
Solid Tumors
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December 13, 2021
Selective STAT3 Degraders Dissect Peripheral T-Cell Lymphomas Vulnerabilities Empowering Personalized Regimens
The 63rd Annual ASH Meeting and Exposition
Liquid Tumors
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December 13, 2021
A First-in-Class STAT3 Degrader KT-333 in Development for Treatment of Hematologic Cancers
The 63rd Annual ASH Meeting and Exposition
Liquid Tumors
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