Read about breakthroughs, clinical advancements, and ongoing work to develop new medicines at Kymera.



Kymera and Sanofi shared positive results for an IRAK4 degrader for hidradenitis suppurativa (HS) and atopic dermatitis (AD), breaking ground to take protein degradation outside the field of oncology and into inflammatory disease indications.
Kymera and Sanofi plan to move ahead with the skin drug that the French drugmaker paid $150 million in cash in 2020 to partner on, after positive Phase I results on the IRAK4 degrader they’ve been working on for a pair of skin conditions.
Kymera Therapeutics has generated the first early clinical evidence that its targeted protein degradation technology works in immune-inflammatory diseases.
KYMR announced positive clinical data from a phase I study evaluating its highly selective, orally bioavailable IRAK4 degrader, KT-474, for the treatment of patients with hidradenitis suppurativa (“HS”) and atopic dermatitis (“AD”).
Kymera’s wellness stipend, instituted at the beginning of the year, is designed to let workers know “we care about them, and want to give them a way to care for themselves,” says Karen Weisbach, vice president of people and culture.
Nello Mainolfi, co-founder, president and CEO of Kymera Therapeutics, has an empty prescription bottle on his desk — a bottle that he hopes to soon fill with with one of the biotech company’s drugs.
The health category of Fast Company’s World Changing Ideas Awards honors medical innovations that save lives, extend longevity, or increase access to care.
Kymera is working on targeted protein degraders. These are orally available small molecule compounds. Many in biopharma are excited about them because they have a clever design that allows them to go after targets that have previously been out of reach for small molecules. Nello Mainolfi, PhD, Founder, President & CEO shares more about Kymera’s work and mission.