Kymera in the News

Read about breakthroughs, clinical advancements, and ongoing work to develop new medicines at Kymera.

Featured Perspectives

December 16, 2025
From Target Selection to POC in Patients: Completing the Initial Human Translation of STAT6 Degradation
Nello Mainolfi, PhD, Founder, President and CEO
February 12, 2025
A Revolution in Immunology: Creating New Possibilities with Oral Medicines
Arsalan Shabbir, MD, PhD, Vice President, Clinical Development
April 24, 2025
A New Era of Possibility: Addressing Coveted Undrugged Targets
Juliet Williams, PhD, Head of Research
Showing 48 news results
December 14, 2022

BioSpace: First Protein Degrader Tested Outside Oncology Yields Promising Results

Kymera and Sanofi shared positive results for an IRAK4 degrader for hidradenitis suppurativa (HS) and atopic dermatitis (AD), breaking ground to take protein degradation outside the field of oncology and into inflammatory disease indications.

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December 14, 2022

Endpoints News: Kymera and Sanofi move ahead with skin drug after promising PhI data

Kymera and Sanofi plan to move ahead with the skin drug that the French drugmaker paid $150 million in cash in 2020 to partner on, after positive Phase I results on the IRAK4 degrader they’ve been working on for a pair of skin conditions.

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December 14, 2022

Fierce Biotech: Sanofi takes inflammatory disease protein degrader forward as Kymera shares glimpse of efficacy

Kymera Therapeutics has generated the first early clinical evidence that its targeted protein degradation technology works in immune-inflammatory diseases.

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December 14, 2022

Nasdaq: Kymera (KYMR) Up on Positive Data From Phase I Study on KT-474

KYMR announced positive clinical data from a phase I study evaluating its highly selective, orally bioavailable IRAK4 degrader, KT-474, for the treatment of patients with hidradenitis suppurativa (“HS”) and atopic dermatitis (“AD”).

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November 30, 2022

Boston Globe: Top Places to Work in Massachusetts 2022

Kymera’s wellness stipend, instituted at the beginning of the year, is designed to let workers know “we care about them, and want to give them a way to care for themselves,” says Karen Weisbach, vice president of people and culture.

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September 6, 2022

PharmaVoice: The 2022 PharmaVoice 100 – Nello Mainolfi

Nello Mainolfi, co-founder, president and CEO of Kymera Therapeutics, has an empty prescription bottle on his desk — a bottle that he hopes to soon fill with with one of the biotech company’s drugs.

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May 3, 2022

FastCompany: These innovative projects are changing the health industry

The health category of Fast Company’s World Changing Ideas Awards honors medical innovations that save lives, extend longevity, or increase access to care.

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December 6, 2021

Timmerman Report: Targeted Small Molecule Protein Degraders, Nello Mainolfi on the Long Run

Kymera is working on targeted protein degraders. These are orally available small molecule compounds. Many in biopharma are excited about them because they have a clever design that allows them to go after targets that have previously been out of reach for small molecules. Nello Mainolfi, PhD, Founder, President & CEO shares more about Kymera’s work and mission.

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Featured Presentations & Publications

September 17, 2025
KT-621, an Oral, Once Daily, Targeted STAT6 Degrader: First-in-Human Phase 1a Safety, Pharmacokinetics, Pharmacodynamics and Th2 Biomarker Effects
European Academy of Dermatology & Venereology (EADV) 2025 – Late Breaking Presentation
October 27, 2025
Potent and Selective Oral IRF5 Degrader, KT-579, Demonstrates In Vitro and In Vivo Activity Comparable or Superior to Approved or Clinically Active Agents in Human Cellular Assays and Lupus Efficacy Models
American College of Rheumatology (ACR) 2025