Potent and Selective Oral STAT6 Degrader, KT-621, Inhibits IL-4 and IL-13 Functions in Human Cells and Blocks Th2 Inflammation in House Dust Mite Models of Asthma Prophylactically and Therapeutically

Potent and Selective Oral STAT6 Degrader, KT-621, Inhibits IL-4 and IL-13 Functions in Human Cells and Blocks Th2 Inflammation in House Dust Mite Models of Asthma Prophylactically and Therapeutically

American Thoracic Society (ATS) 2025

Amy Wang, Bin Yang, Karen Yuan, Alamgir Hossain, Huijun Dong, Anand Ramanathan, Bruce Follows, Sean Zhu, Chris Browne, Andreas Harsch, Ralf Schmidt, Mike Weis, Rupa Sawant, Bradley Enerson, Jing Yuan, Richard Miller, Matt Weiss, Nello Mainolfi