Consultant, Medicinal Chemistry
<h3><strong>Who we are:</strong></h3>
<p>Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit <a href="https://www.kymeratx.com" target="_blank">www.kymeratx.com</a> or follow us on <a href="https://twitter.com/KymeraTx?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor" target="_blank">X (formerly Twitter)</a> or <a href="http://www.linkedin.com/company/kymeratherapeutics" target="_blank">LinkedIn</a>. </p>
<p> </p>
<h3><strong>How we work:</strong></h3>
<ul>
<li><strong>PIONEER</strong>: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.</li>
<li><strong>COLLABORATE</strong>: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.</li>
<li><strong>BELONG</strong>: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.</li>
</ul>
<p> </p>
<h3><strong>How you’ll make an impact:</strong></h3>
<ul>
<li>Provide senior-level medicinal chemistry expertise on a part-time consulting basis.</li>
<li>Support hit-to-lead and lead optimization strategy, including compound design and SAR analysis.</li>
<li>Serve as scientific partner to internal chemistry leads.</li>
<li>Review and provide feedback on program chemistry data packages.</li>
<li>Recommend paths forward at project inflection points.</li>
</ul>
<h3><strong>Skills and experience you’ll bring:</strong></h3>
<ul>
<li>PhD in organic/medicinal chemistry with 20+ years in drug discovery, including small molecule optimization.</li>
<li>Proven experience delivering preclinical candidates.</li>
<li>Deep knowledge of synthetic chemistry and medicinal chemistry principles.</li>
<li>Prior experience advising biotech/pharma discovery teams as a consultant or advisor.</li>
<li>Prior exposure to DEL or fragment-based drug discovery a plus.</li>
<li>Ability to work independently while communicating effectively with internal stakeholders.</li>
</ul>
<p> </p>
<p> </p>
<p><strong><em><span class="ui-provider a b c d e f g h i j k l m n o p q r s t u v w x y z ab ac ae af ag ah ai aj ak">Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.</span></em></strong></p>
<p> </p>