The Potent and Selective Oral STAT6 Degrader, KT-621, Affects Gene Transcripts in Human Keratinocytes as Effectively as Dupilumab, and Blocks Th2 Inflammation in Atopic Dermatitis and Asthma Mouse Models

September 17, 2025

The Potent and Selective Oral STAT6 Degrader, KT-621, Affects Gene Transcripts in Human Keratinocytes as Effectively as Dupilumab, and Blocks Th2 Inflammation in Atopic Dermatitis and Asthma Mouse Models

European Academy of Dermatology & Venereology (EADV) 2025

Amy Wang, Bin Yang, Karen Yuan, Alamgir Hossain, Rahul Karnik, James Shaw, Huijun Dong, Bruce Follows, Chris Browne, Ralf Schmidt, Rupa Sawant, Bradley Enerson, Chad Nivens, Nello Mainolfi

Kymera EADV Poster Image 2025
Area of Focus
Immunology
Programs
STAT6 (KT-621)
Indications
Atopic Dermatitis (AD) Asthma
Development Stage
Pre-clinical Data
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