Potent and Selective Oral IRF5 Degrader, KT-579, Blocks Pro-Inflammatory Cytokines and Reduces Joint Swelling in Rodent Models of Rheumatoid Arthritis

Potent and Selective Oral IRF5 Degrader, KT-579, Blocks Pro-Inflammatory Cytokines and Reduces Joint Swelling in Rodent Models of Rheumatoid Arthritis

American College of Rheumatology (ACR) 2025

Ryan Camire, Yi Zhang, Virginia Massa, Jordan Leedberg, Erik Corcoran, Emily Lurier, Christopher Carroll, Chris Ho, Dapeng Chen, Bradley Enerson, Revonda Mehovic, Ziyan Zhao, Lincoln Howarth, Susanne Breitkopf, Sarah Martinez, Melissa Ford, Xue Fei, Murugappan Sathappa, Juliet Williams, Matthew Weiss, Arsalan Shabbir, Nello Mainolfi, Veronica Campbell